{
  "@context": {
    "@vocab": "https://root-ld.org/spec/1.0/",
    "schema": "https://schema.org/",
    "bs": "https://boisestandard.org/vocab#",
    "rld": "https://root-ld.org/",
    "xsd": "http://www.w3.org/2001/XMLSchema#"
  },
  "@type": "rld:RootLD",
  "@id": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld",
  "rld:specVersion": "1.0",
  "rld:anchor": {
    "@type": "rld:Anchor",
    "rld:uuid": "c7d51130-e98e-4e25-9735-05404e27cbb0",
    "rld:federationId": "bs-c7d51130",
    "rld:contentHash": "cc7259c1a8f1e33a08a899ce0f1968d6ba2aad506ad6425f8b4299d7ddafa041",
    "rld:primarySource": "https://rapalimus-gel.nobelpark.jp/",
    "rld:sourceVerified": true,
    "rld:generationMethod": "crawl_extract_v1",
    "rld:specVersion": "1.0",
    "rld:queuedAt": "2026-05-26T20:36:55.657956+00:00",
    "rld:mintedAt": "2026-07-03T14:57:01.936363+00:00",
    "rld:sequence": 0,
    "rld:pipeline": "refinery-boise-v1.0.0",
    "rld:domainSignature": "rapalimus-gel.nobelpark.jp",
    "rld:manifest": {
      "bs:schemaTypes": [],
      "bs:primaryType": "WebPage",
      "bs:coverageScore": 0.0,
      "bs:coverageLabel": "none",
      "bs:propCount": 0,
      "bs:blockCount": 0,
      "bs:ancestorCount": 0,
      "bs:negativeSpaceCount": 11,
      "bs:hasTopo": true,
      "bs:hasKeywords": true,
      "bs:hasSchema": false,
      "bs:hasEdges": false,
      "bs:hasGeo": false,
      "bs:hasAtomicAnswer": false,
      "bs:hasCommon": false,
      "bs:hasUncommon": false,
      "bs:edgeCount": 0,
      "bs:topologyCategory": "long",
      "bs:totalTokens": 2012,
      "bs:typeTokenRatio": 0.3544,
      "bs:lastPassDate": null,
      "rld:toc": {
        "body": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-body",
        "schema": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-body/schema",
        "topology": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-body/topology",
        "keywords": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-body/keywords",
        "geo": null,
        "atomicAnswer": null,
        "schemaGraph": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#schema-graph",
        "manifest": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp/manifest.json",
        "rootLd": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp/root-ld.json",
        "edges": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-recursive/edges",
        "commonEdges": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-recursive/common",
        "uncommonEdges": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-recursive/uncommon"
      }
    },
    "rld:linkPod": {
      "webPageUrl": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp",
      "manifestUrl": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp/manifest.json",
      "rootLdUrl": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp/root-ld.json",
      "canonicalUrl": "https://rapalimus-gel.nobelpark.jp/",
      "tldGraphEdgeUrl": "https://boisestandard.org/registry/tld/ledger/jp",
      "schemaVocabUrl": "https://boisestandard.org/schema/official_vocab.json",
      "schemaVocabHumanUrl": "https://boisestandard.org/schema/official_vocab/",
      "schemaStandardUrl": "https://boisestandard.org/schema/",
      "officialVocabUrl": "https://schema.org/version/latest/schemaorg-current-https.jsonld"
    }
  },
  "rld:body": {
    "@type": "rld:Body",
    "@id": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-body",
    "rld:frozenAt": "2026-07-03T14:57:01.936363+00:00",
    "bs:identity": {
      "domain": "rapalimus-gel.nobelpark.jp",
      "slug": "rapalimus-gel-nobelpark-jp",
      "tld": "jp",
      "canonicalUrl": "https://rapalimus-gel.nobelpark.jp/",
      "finalUrl": "https://rapalimus-gel.nobelpark.jp/",
      "statusCode": 200,
      "sslValid": true,
      "serverHeader": "Apache",
      "responseTimeMs": 5376,
      "redirectChain": []
    },
    "bs:seo": {
      "@id": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-body/seo",
      "title": "ラパリムスゲル 結節性硬化症 情報サイト|ノーベルファーマ",
      "h1": "",
      "metaDescription": "ラパリムスゲル0.2%は、結節性硬化症（TSC）に伴う皮膚病変に対し、非侵襲的に使用できる局所投与の世界初の治療剤です。",
      "canonicalUrl": "",
      "langDeclared": "",
      "wordCount": 81,
      "ogTitle": "",
      "ogDescription": ""
    },
    "bs:schema": {
      "@id": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-body/schema",
      "typesFound": [],
      "interiorTypes": [],
      "blockCount": 0,
      "propCount": 0,
      "coverageScore": 0.0,
      "coverageLabel": "none",
      "gapList": [],
      "parentTypes": [],
      "siblingTypes": [],
      "childTypes": [],
      "negativeTypeSpace": [
        "Action",
        "BioChemEntity",
        "CreativeWork",
        "Event",
        "Intangible",
        "MedicalEntity",
        "Organization",
        "Person",
        "Place",
        "Product",
        "Taxon"
      ],
      "negativeTypeSpaceNote": "These schema types have no structural connection to the declared type branch of the schema.org graph. Graph position measurement — not inference. Constitutional Law VI: the absence of connection is a pattern waiting to be read. Law III: meaning is yours.",
      "vocabVersion": "2.0.0",
      "analyzedAt": "2026-07-03T14:57:15.841895+00:00",
      "graphEdgeUrls": [],
      "schemaGraphRef": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#schema-graph"
    },
    "bs:semantic": {
      "@id": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-body/keywords",
      "topWords": [
        "tuberous",
        "sclerosis",
        "pick",
        "pubmed",
        "complex",
        "topical",
        "nobelpharma",
        "sirolimus",
        "dermatol",
        "javascript",
        "gel",
        "facial",
        "rapamycin",
        "enable",
        "pdf",
        "reader",
        "angiofibromas",
        "management",
        "related",
        "analysis",
        "treatment",
        "wataya",
        "kaneda",
        "surveillance",
        "adobe",
        "efficacy",
        "patients",
        "clinical",
        "jama",
        "therapy",
        "medpass",
        "cutaneous",
        "manifestations",
        "interim",
        "postmarketing",
        "japan",
        "angiofibroma",
        "tsc",
        "skin",
        "trial"
      ],
      "wordCount": 40,
      "note": "Top words by frequency from homepage + interior pages after stop-word removal. No language classification. No dictionary matching. Pure signal from what the entity chose to say about itself. Constitutional Law III."
    },
    "bs:topologyFingerprint": {
      "@id": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-body/topology",
      "modelVersion": "1.0.0",
      "extractedTextHash": "8bfb768efe6eccea1d27b6d08315530f2d07ac0671dfa32a0093f005e5c736cb",
      "extractionTimestamp": "2026-07-03T14:57:15.822665+00:00",
      "textLengthCategory": "long",
      "rawTextLength": 18151,
      "character": {
        "totalCharacters": 18151,
        "uniqueCharacters": 631,
        "characterDiversityRatio": 0.034764,
        "nonAsciiRatio": 0.416506,
        "uppercaseRatio": 0.138052,
        "numericRatio": 0.092943,
        "characterEntropy": 4.967247,
        "mostFrequentCharacter": "0",
        "leastFrequentCharacter": "項"
      },
      "token": {
        "totalTokens": 2012,
        "uniqueTokens": 713,
        "typeTokenRatio": 0.354374,
        "averageTokenLength": 8.003479,
        "maxTokenLength": 75,
        "longestToken": "https%3A%2F%2Frapalimus-gel.nobelpark.jp%2Fseminar%2F%23webseminar_20230928",
        "hapaxLegomenaCount": 467
      },
      "punctuation": {
        "punctuationDensity": 0.038345,
        "commaToPeriodRatio": 0.1667,
        "punctuationEntropy": 1.552037,
        "avgInterPeriodDist": 83.976744,
        "avgInterCommaDist": 486.742857,
        "semicolonDensity": 0.015591,
        "questionMarkDensity": 0.0
      },
      "sentence": {
        "sentenceCount": 40,
        "avgSentenceLengthTokens": 50.3,
        "skewnessSentenceLength": 5.620555,
        "kurtosisSentenceLength": 31.112246,
        "longSentenceRatio": 0.1,
        "firstToMeanLengthRatio": 3.837,
        "lastToMeanLengthRatio": 0.0596
      },
      "paragraph": {
        "paragraphCount": 8,
        "avgParagraphLengthTokens": 251.5,
        "singleSentenceParagraphRatio": 0.875
      },
      "document": {
        "capitalTokenRatio": 0.170477,
        "repetitionScore": 0.767893,
        "bigramRepetitionScore": 0.551964,
        "hapaxToTypeRatio": 0.654979
      }
    },
    "bs:ratioSignals": {
      "schemaDensity": 0.0,
      "navRatio": 0.2857,
      "contentToStructureRatio": 0.069,
      "externalTldDiversity": 1,
      "selfDeclarationCoherence": 0.1,
      "schemaToNavigationAlignment": 0.0,
      "javascriptSurfaceRatio": 0.0,
      "urlDepthDistribution": {
        "depth_0": 1,
        "depth_1": 14,
        "depth_2": 9,
        "depth_3plus": 11
      },
      "note": "Eight deterministic measurements. No judgment. The gap is the signal. Every value traces to a specific pipeline stage. Constitutional Law I: full provenance."
    },
    "bs:navigation": {
      "totalUrlCount": 35,
      "navUrlCount": 10,
      "deadUrls": [],
      "externalTlds": [
        "jp"
      ],
      "interiorPageCount": 13,
      "interiorWordCount": 1931,
      "jsSurfaceRatio": 0.0
    },
    "bs:provenance": {
      "securityLabel": "MINIMAL",
      "httpsEnforced": true,
      "hstsDetected": false,
      "cspDetected": false,
      "freshnessLabel": "STALE",
      "latestYearInContent": 2024,
      "techStack": {
        "cms": null,
        "cdn": null,
        "web_server": "Apache",
        "analytics": [
          "Google Analytics",
          "Google Tag Manager"
        ],
        "frameworks": []
      }
    },
    "bs:graphEdges": {
      "totalEdges": 1,
      "tldEdges": 1,
      "schemaTypeEdges": 0,
      "schemaPropEdges": 0,
      "note": "Graph edges this entity leaves on the Boise Standard graph. Each edge records this entity's connection to a vocabulary node — a schema type, a schema property, or a TLD. Constitutional Law V: what two things share is a thing. The graph builds itself."
    },
    "bs:pipeline": {
      "extractorVersion": "refinery-boise-v1.0.0",
      "extract1TimeS": 7.37,
      "extract2TimeS": 6.51,
      "topologyTimeS": 0.019,
      "schemaTimeS": 0.0,
      "atomicAnswerTimeS": 0.0,
      "totalPipelineS": 13.91,
      "attemptCount": 1,
      "braidName": "run-20260629-203336"
    }
  },
  "rld:recursive": {
    "@type": "rld:Recursive",
    "@id": "https://boisestandard.org/web/rapalimus-gel-nobelpark-jp#root-ld-recursive",
    "rld:edgeCount": 0,
    "rld:edges": [],
    "rld:appendedAt": [],
    "rld:mintNote": "Recursive layer initialized at mint. Empty by design. Edges form through accumulated corpus passes — common edges (Law V), uncommon edges (Law VI), topology cluster scores, and for Boise Standard: jurisdictional and supply-chain edges. The graph builds itself. Constitutional Law VII — Torus.",
    "rld:substrateNote": "Topology cluster membership and geometric coordinates in shape space populate here when corpus depth makes the measurements meaningful.",
    "rld:recursiveSpecUrl": "https://root-ld.org/spec/1.0/recursive",
    "rld:initializedAt": "2026-07-03T14:57:16.158070+00:00"
  }
}